Zyrtec is a second generation antihistamine that works quickly after taking by mouth. It lasts for about 24 hours and should be taken on an empty stomach to avoid food interference. Zyrtec begins to work at hour 1 on the first day you take it. How long does zyrtec last? Is it okay to take zyrtec over a long period of time?
Antihistamines, like claritin (loratadine) and zyrtec (cetirizine), start working within a few hours. They can prevent symptoms if you take them daily. Nasal steroid sprays, like flonase (fluticasone propionate), can take up to 2 weeks to fully kick in. How long does zyrtec take to work? Generally, zyrtec starts working in about 20 to 60 minutes if you take it on an empty stomach. It may take slightly longer (up to 90 minutes) if you take it with food. How long does it take for cetirizine (zyrtec) to work and how long does it last? Expand_more it takes about 20 to 60 minutes for cetirizine (zyrtec) to start working and lasts all day.
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